心胸外科医院感染的临床现状及病原菌耐药性探讨

目的 探讨医院心胸外科医院感染的临床现状与病原菌耐药性,为预防与控制医院感染提供参考依据.方法 对医院315例心胸外科发生医院感染的患者病历进行回顾性调查.结果 315例患者均患有严重的原发基础疾病；感染部位以呼吸道感染发病率最高,占64.8％；病原菌以革兰阴性菌为主,占70.1％;革兰阳性菌占23.2％；真菌占6.7％；其中铜绿假单胞菌(PAE)与鲍氏不动杆菌(ABA)分离率最高,分别占24.7％、18.1％;肺炎克雷伯菌(KPN)居第3位占12.7~革兰阳性菌中耐甲氧西林金黄色葡萄球菌(MRSA)占金黄色葡萄球菌总株数的51.3％;多数病原菌显示严重的耐药性.结论 务必制定有效的干预措施,降低医院感染发病率.

Clinical status of nosocomial infections in department of cardiothoracic surgery and antimicrobial resistance

OBJECTIVE To approach the clinical status and antimicrobial resistance of hospital infection in department of cardiothoracic surgery so as to provide reference for clinical prevention and control of nosocomial infections.METHODS The retrospective investigation was performed for the medical records of 315 patients with nosocomial infections admitted in the department of cardiothoracic surgery.RESULTS All 315 patients had severe primary diseases;the incidence of respiratory tract infections was the highest(64.8%);the majority of pathogens were gram-negative bacteria,accounting for 70.1%,gram-positive cocci accounted for 23.2%,and fungi accounted for 6.7%.The isolation rates of Pseudomonas aeruginosa(24.7%) and Acinetobacter baumannii(18.1%) were the highest,followed by Klebsiella pneumoniae(12.7%).Of gram-positive bacteria,methicillin-resistant Staphylococcus aureus(MRSA) accounted for 51.3% among Staphylococcus aureus;the majority of pathogenic bacteria showed serious drug resistance.CONCLUSION It is necessary to institute effective interventions to reduce the incidence of nosocomial infections.