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血液透析用水及透析液质量监测结果分析
引用本文:陈秀强,韦曦,刘丽珍,温黎青,余坤,吴媛,石庆源. 血液透析用水及透析液质量监测结果分析[J]. 中华医院感染学杂志, 2012, 22(3): 550-551
作者姓名:陈秀强  韦曦  刘丽珍  温黎青  余坤  吴媛  石庆源
作者单位:1. 柳州市肿瘤医院肾内科,广西柳州,545006
2. 柳州市人民医院药剂科,广西柳州,545006
3. 柳州市人民医院肾内科,广西柳州,545006
4. 柳州市人民医院血透中心,,广西柳州545006
5. 广西医科大学药学院药学系,广西南宁,530021
6. 天津医科大学药学院药学系,天津,300275
摘    要:目的 对血液透析用水、透析液开展质量监测.方法 按《中国药典》方法做微生物限度、细菌内毒素检查、化学污染物等检验.结果 微生物学检验结果符合国家食品药品监督管理局发布的医药行业标准YY0572-2005中规定的要求,但经贮水容器和输水管路出口的透析用水中,细菌内毒素由0.125 Eu/ml增加至0.25 Eu/ml,真菌数由10 CFU/200 ml增加至150CFU/200 ml,硝酸盐浓度增高约5倍.结论 透析用水、透析液应每日现制现用,注意消毒和冲洗各输液管路.

关 键 词:透析用水  透析液  微生物  细菌内毒素  化学污染物

Monitoring and analysis of quality control of hemodialysis water and dialysis fluid
CHEN Xiu-qiang , WEI Xi , LIU Li-zhen , WEN Li-qing , YU Kun , WU Yuan , SHI Qing-yuan. Monitoring and analysis of quality control of hemodialysis water and dialysis fluid[J]. Chinese Journal of Nosocomiology, 2012, 22(3): 550-551
Authors:CHEN Xiu-qiang    WEI Xi    LIU Li-zhen    WEN Li-qing    YU Kun    WU Yuan    SHI Qing-yuan
Affiliation:(Liuzhou Cancer Hospital,Liuzhou,Guangxi 545006,China)
Abstract:OBJECTIVE To develop the quality surveillance of hemodialysis water and dialysis fluid. METHODS According to standard method of Chinese Pharmacopoeia,microbial limit,bacterial endotoxin and chemical pollutant were examined. RESULTS The monitoring results showed that the microbial limit was in line with the standard of YY0572-2005 published by SFDA.The bacterial endotoxin increased from 0.125 Eu/ml to 0.25 Eu/ml,the mold increased from 10/200 ml to 150/200 ml and the concentration of nitrate increased 5 times in dialysis water exported from water containers and water pipes. CONCLUSION The hemodialysis fluid should be prepared daily,all infusion lines should be washed and sterilized.
Keywords:Hemodialysis water  Hemodialysis fluid  Microbe  Bacterial endotoxin  Chemical pollutant
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