肝硬化合并医院感染的危险因素分析

目的 探讨肝硬化患者合并医院感染的相关危险因素.方法 选择2008年6月—2011年9月医院收治的肝硬化合并医院感染患者613例,所有入选病例经明确诊断后详细收集和记录患者的性别、年龄、既往病史、并发症等相关危险因素,并充分结合实验室及其特殊检查进行回顾性分析.结果 613例肝硬化患者中,92例发生医院感染,感染率为15.01％年龄大、白蛋白低、住院时间长、有侵入性操作、有并发症、有合并症、预防性应用抗菌药物为医院感染的危险因素,其中年龄＞40岁患者感染率为19.75％,白蛋白＜3.0 g/dl患者感染率为19.71％,住院时间≥20 d患者感染率为21.43％,有侵入性操作感染率为18.23％,有并发症、合并症患者感染率为18.05％、25.23％,预防性应用抗菌药物患者感染率为19.61％.结论 只有充分重视引起肝硬化患者合并医院感染的危险因素,并据此积极采取多角度、全方位的防治措施,才能尽可能的将肝硬化合并医院感染的比率控制在最低范围.

Risk factors for liver cirrhosis combined with nosocomial infections

OBJECTIVE To probe into the related risk factors for liver cirrhosis combined with nosocomial infections.METHODS From Jun 2008 to Sep 2011,a total of 613 liver cirrhosis patients combined with nosocomial infections were selected.All of the enrolled cases after detailed diagnosed,were collected and recorded The related factors for all of the enrolled cases,including the gender,age,past medical history,and complications,were carefully collected and recorded after the confirmed diagnosis,and then retrospectively analyzed through fully combining with the laboratory and the special test.RESULTS Of 613 patients with liver cirrhosis,nosocomial infections occurred in 92 patients with the infection rate of 15.01%;the advanced age,low albumin,long hospital stay,invasive operation,complications,complicated disease,and prophylactic use of antibiotics were the risk factors for nosocomial infections,the infection rate of the patients aged more than 40 years was 19.75%,the patients with albumin less than3.0 g/dl 19.71%,the patients with hospital stay longer than 20 d 21.43%,the patients with invasive operations 18.23%,the patients with complications or complicated diseases18.05%,25.23%,the patient with prophylactic use of antibiotics 19.61%.CONCLUSION Only by focusing on the risk factors for nosocomial infections in the patients with liver cirrhosis and taking actions in a multiperspective and comprehensive manner can we minimize the incidence rate of nosocomial infections in patients with liver cirrhosis.