肺泡灌洗液中铜绿假单胞菌的分布及耐药性分析

目的 了解肺泡灌洗液中铜绿假单胞菌在病区的分布及耐药性,为临床合理用药提供依据.方法 采用美国Microscan Autoscan-4微生物分析仪对细菌做鉴定和药敏试验,应用WHONET 5.4软件对数据进行分析.结果 铜绿假单胞菌主要分布于神经外科、ICU、呼吸科,检出率分别为46.4％、25.0％、14.3％,各病区分离菌对阿米卡星耐药率最低,对其他8种抗菌药物的耐药率略有差异.结论 肺泡灌洗液的主要病原菌为铜绿假单胞菌,不同病区的细菌耐药特点存在差异,合理用药是控制感染的关键.

Distribution and drug resistance of Pseudomonas aeruginosa in bronchoalveolar lavage fluid

OBJECTIVE To understand the distribution and drug resistance of Pseudomonas aeruginosa in the bronchoalveolar lavage fluid and offer basis for clinical rational medication.METHODS The identification and drug susceptibility testing of the bacteria were performed with Microscan Autoscan-4,and the data were analyzed with WHONET 5.4.RESULTS P.aeruginosa isolates were mainly isolated from department of neurosurgery,ICU,and respiratory department with detection rates of 46.4%,25.0% and 14.3%,respectively;of all the isolates from various departments,the resistance rate of P.aeruginosa against amikacin was the lowest,there was a little difference in the drug resistance to other 8 antibiotics.CONCLUSION The main pathogenic bacteria in the bronchoalveolar lavage fluid are P.aeruginosa isolates,there is difference in bacterial resistance among various wards,rational use of antibiotics is the key to control infections.