耐万古霉素肠球菌的目标性监测与分析

目的 了解临床耐万古霉素肠球菌的分离和耐药性,探索耐万古霉素肠球菌感染病例的监控措施.方法 对2010年医院临床分离的病原菌进行目标性监测,统计耐万古霉素肠球菌的株数以及耐药性,并对临床耐万古霉素肠球菌感染病例实施监控.结果 共分离出肠球菌属582株,其中耐万古霉素肠球菌占2.20％,对抗菌药物耐药率较高；全院未发生耐万古霉素肠球菌的暴发和流行.结论 耐万古霉素肠球菌分离株数较多,耐药率较高,应该加强临床合理使用抗菌药物的管理,对耐万古霉素肠球菌感染病例实施监控,预防和减少多药耐药菌的产生,控制医院感染.

Targeted surveillance for vancomycin resistance of Enterococci

OBJECTIVE To understand of the isolation and drug resistance of vancomycin-resistant Enterococci(VRE) so as to explore measures for the surveillance of VRE infection.METHODS Targeted surveillance for clinical isolated pathogens in 2010 was performed.Statistical analysis of the number of VRE was performed and their drug resistance was studied.Cinical surveillance for VRE infection was carried out.RESULTS There were 582 strains of Enterococci isolated,among which VRE accounted for 2.20%,with relatively high drug resistance.Outbreak and prevalence of VRE in hospital were not detected.CONCLUSION VRE strains are relatively large in number,and the drug resistance rate is relatively high.To prevent and reduce multidrug-resistant strains and control nosocomial infection,rational use of antimicrobial drugs should be highlighted and surveillance for VRE infection should be implemented.