Distribution of β-endorphin in normal and schizophrenic human brains |
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Authors: | STAFFORD L LIGHTMAN ERNEST G SPOKES GIUSEPPE A SAGNELLA DAVID GORDON EDWARD D BIRD |
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Institution: | Medical Unit, St Mary's Hospital Medical School, London, W2, and Department of Neurological Surgery and Neurology, Addenbrookes Hospital, Cambridge |
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Abstract: | beta-Endorphin was measured by radioimmunoassay in post-mortem human brains. Samples of brain were taken from five discrete areas, both from control brains and brains of schizophrenic patients. No difference in beta-endorphin levels was found in these two groups of brains. beta-Endorphin was confirmed to be widely distributed in the brain, but there were considerable differences in the concentrations in different areas. |
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Keywords: | Human brain β-endorphin schizophrenia |
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