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Distribution of β-endorphin in normal and schizophrenic human brains
Authors:STAFFORD L LIGHTMAN  ERNEST G SPOKES  GIUSEPPE A SAGNELLA  DAVID GORDON  EDWARD D BIRD
Institution:Medical Unit, St Mary's Hospital Medical School, London, W2, and Department of Neurological Surgery and Neurology, Addenbrookes Hospital, Cambridge
Abstract:beta-Endorphin was measured by radioimmunoassay in post-mortem human brains. Samples of brain were taken from five discrete areas, both from control brains and brains of schizophrenic patients. No difference in beta-endorphin levels was found in these two groups of brains. beta-Endorphin was confirmed to be widely distributed in the brain, but there were considerable differences in the concentrations in different areas.
Keywords:Human brain              β-endorphin  schizophrenia
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