| 两种方案控制顺铂所致恶心呕吐的成本-效果分析 |
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| 引用本文： | 穆海川,刘松青.两种方案控制顺铂所致恶心呕吐的成本-效果分析[J].中国药业,2006,15(8):38-38. |
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| 作者姓名： | 穆海川 刘松青 |
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| 作者单位： | 第三军医大学附属西南医院药学部,重庆,400038 |
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| 摘 要： | 目的 通过对两种5-羟色胺3（5-HT3）受体拮抗剂控制顺铂所致呕吐治疗方案的成本-效果分析,为临床提供疗效好而经济成本低的方案.方法 将48例顺铂化疗者随机分为2组,分别给予盐酸格拉司琼和盐酸托烷司琼止吐,运用药物经济学成本-效果方法进行评价.结果 盐酸格拉司琼和盐酸托烷司琼在治疗顺铂所致呕吐反应的疗效及安全性检测方面均无显著性差异（P＞0.05）.结论 盐酸格拉司琼治疗方案因花费较少而成为最佳方案.
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| 关 键 词： | 成本-效果分析 顺铂 呕吐 盐酸格拉司琼 盐酸托烷司琼 |
| 文章编号： | 1006-4931(2006)08-0038-01 |
| 收稿时间： | 02 16 2006 12:00AM |
| 修稿时间： | 2006年2月16日 |
Cost-effectiveness Analysis of Two Preventing Schemes for Cisplatin-induced Vomiting |
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| Mu Haichuan,Liu Songqing.Cost-effectiveness Analysis of Two Preventing Schemes for Cisplatin-induced Vomiting[J].China Pharmaceuticals,2006,15(8):38-38. |
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| Authors: | Mu Haichuan Liu Songqing |
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| Institution: | Department of Pharmacy, Southwest Hospital, Third Military Medical University, Chongqing, China 400038 |
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| Abstract: | Objective To discuss the cost-effectiveness of two 5-HT3 receptor suppressant preventing schemes for cisplatin-induced vomiting.Methods 48 cases receiving cisplatin chemotherapy were randomly divided into two groups according to the preventing schemes received:group A,tropisetron hydrochloride;group B,granisetron hydrochloride.The data was evaluated using pharmacoeconomic cost-effectiveness analysis.Results There was no significant difference between the two groups in respect of targets of srcurity and adverse effects(P > 0.05).Conclusion The granisetron hydrochloride scheme is the most rational one. |
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| Keywords: | cost- effectiveness analysis cisplatin vomiting tropisetron hydrochloride granisetron hydrochloride |
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