| P21和P185在颊粘膜上皮良性和恶性病变中的表达及意义 |
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| 引用本文： | 杨连君 金岩 等. P21和P185在颊粘膜上皮良性和恶性病变中的表达及意义[J]. 华西口腔医学杂志, 1998, 16(1): 0-22,T002 |
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| 作者姓名： | 杨连君 金岩 等 |
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| 作者单位： | [1]第四军医大学病理学教研室710032 [2]口腔医学院病理科 |
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| 摘 要： | 采用免疫组化ABC法检测P21和P185在正常颊粘膜上皮，慢性非特异性炎症病变、镤状细胞癌及其癌旁组织中的表达，并进行图像分析，结果显示，P21和P185在鳞癌和部分癌旁组织中的表达明显高于正常颊粘膜上皮和炎症病变，二者具有明显的相关性，提示P21和P18与颊粘膜上皮恶变有相关性。
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| 关 键 词： | 颊粘膜 鳞状细胞癌 P21 P185 免疫组织化学 图像分析 |
| 收稿时间： | 1998-02-25 |
Expression of P21 and P185 in Benign and Malignant Epithelia of Cheek Mucosa |
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| L Yang,Y Jin,X Si. Expression of P21 and P185 in Benign and Malignant Epithelia of Cheek Mucosa[J]. West China journal of stomatology, 1998, 16(1): 0-22,T002 |
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| Authors: | L Yang Y Jin X Si |
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| Affiliation: | Department of Pathology, Fourth Military Medical University. |
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| Abstract: | To analyze the expression of P21 and P185 in normal epithelia, chronic non-specific inflammatory epithelia, squamous cell carcinoma and epithelia immediately adjacent to carcinoma of cheek mucosa, immunohistochemistry technique and image analysis technique were used. The results showed: there was excellently higher expression of P21 and P185 in squamous cell carcinoma and epithelia immediately adjacent to carcinoma than in normal and inflammatory epithelia of cheek mucosa, which were compactly correlative. |
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| Keywords: | cheek mucosa P21 P185 squamous cell carcinoma immunohistochemistry image analysis |
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