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| 北柴胡及春柴胡挥发油的解热作用比较 | |
| 引用本文： | 谢东浩,贾晓斌,蔡宝昌,张林松,袁冬平.北柴胡及春柴胡挥发油的解热作用比较[J].中国医院药学杂志,2007,27(4):502-504. |
| 作者姓名： | 谢东浩 贾晓斌 蔡宝昌 张林松 袁冬平 |
| 作者单位： | 1. 南京中医药大学,江苏,南京,210046;江苏大学附属医院药剂科,江苏,镇江,212001 2. 江苏省中医药研究院,江苏,南京,210028 3. 南京中医药大学,江苏,南京,210046 4. 江苏省镇江市药品检验所,江苏,镇江,212001 |
| 基金项目： | 江苏省中医药科技研究专项科研项目（编号：H05007） |
| 摘 要： | 目的：通过解热作用比较北柴胡及春柴胡挥发油的差异。方法：采用干酵母所致大鼠发热模型及内毒素所致家兔发热模型，观察北柴胡及春柴胡的解热作用。结果：北柴胡及春柴胡均可降低干酵母所致大鼠体温升高和降低内毒素所致家兔体温升高，与模型组比较差异有显著性（P〈0．05）。结论：北柴胡及春柴胡均具有良好的解热作用，提示春柴胡在临床上可以替换北柴胡。 |
| 关 键 词： | 北柴胡 春柴胡 解热作用 |
| 文章编号： | 1001-5213(2007)04-0502-03 |
| 修稿时间： | 2006-12-13 |
Comparative study on antipyretic effect of naphtha in Bupleurum chinense DC and Bupleurum scorzonerifolium Willd |
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| XIE Dong-hao ,JIA Xiao-bin , CAI Bao-chang, ZHANG Lin-song.Comparative study on antipyretic effect of naphtha in Bupleurum chinense DC and Bupleurum scorzonerifolium Willd[J].Chinese Journal of Hospital Pharmacy,2007,27(4):502-504. | |
| Authors: | XIE Dong-hao JIA Xiao-bin CAI Bao-chang ZHANG Lin-song |
| Institution: | 1. Nanjing University of TCM, Jiangsu Nanjing 210046,China; 2. Affiliated Hospital of Jiangsu University, Jiangsu Zhenjiang 212001 ,China;3. Jiangsu Provincial Institute of TCM, Jiangsu Nanjing 210028,China;4. Zhenjiang Institute for Drug Control, Jiangsu Zhenjiang 212003,China |
| Abstract: | OBJECTIVE To study the fever relieving effect and compare the content difference of naphtha in Bupleurum chinense DC and Bupleurum scorzonerifolium Willd.METHODS The model of fevered rat was prepared by yeast injected subcutaneously and the model of fevered rabbit was prepared by endotoxin injected intravenously.The difference between naphtha in Bupleurum chinense DC and Bupleurum scorzonerifolium Willd.was observed.RESULTS Both Bupleurum chinense DC and Bupleurum scorzonerifolium Willd.Could decrease animal fever induced by yeast in rat and endotoxin in rabbit.According to the results,the potency of Bupleurum chinense DC was lower than Bupleurum scorzonerifolium Willd,There was significant difference between treated groups and model groups(P<0.05).CONCLUSION There are good antipyretic effect between Bupleurum chinense DC and Bupleurum scorzonerifolium Willd and,moreover,Bupleurum scorzonerifolium Willd is better than another one. |
| Keywords: | Bupleurum chinense DC Bupleurum scorzonerifolium Willd antipyretic effect |
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