| 蚕蛹虫草抗肿瘤作用的研究 |
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| 引用本文： | 刘洁,陈正,杨旭,谷恒生,范贵华. 蚕蛹虫草抗肿瘤作用的研究[J]. 吉林大学学报(医学版), 1992, 0(5) |
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| 作者姓名： | 刘洁 陈正 杨旭 谷恒生 范贵华 |
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| 作者单位： | 白求恩医科大学基础医学院药理教研室(刘洁，陈正，杨旭)，吉林省蚕业科学研究所(谷恒生)，吉林省蚕业科学研究所(范贵华) |
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| 摘 要： | 蚕蛹虫草水煎剂给予小白鼠灌胃,实验证明,具有明显抑制小鼠S_(180)瘤块生长,延长荷瘤小鼠寿命,降低小鼠荷瘤率;明显抑制小鼠Lewis肺癌原发灶生长和自发肺部转移;其作用机理通过提高机体免疫力,促进小鼠脾淋巴细胞转化率,激活腹腔巨噬细胞吞噬活性。体外实验表明,具有直接抑制喉癌细胞生长及集落形成。蚕蛹虫草的作用在性质及强度上与冬虫夏草相近。
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| 关 键 词： | 蚕蛹虫草 冬虫夏草 S_(180) Lewis肺癌 巨噬细胞 |
ANTICARCINOGENIC EFFECT OF CORDYCEPS MILITARIS LINK |
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| Liu Jie,Chen Zheng,Yang Xu Gu Hengcheng,Yuan Guihua. ANTICARCINOGENIC EFFECT OF CORDYCEPS MILITARIS LINK[J]. Journal of Jilin University: Med Ed, 1992, 0(5) |
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| Authors: | Liu Jie Chen Zheng Yang Xu Gu Hengcheng Yuan Guihua |
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| Abstract: | In mice implanted with S180, decoction of Cordyceps Militaris Link given orally inhibited growth of the tumor, prolonged the survival period of the animals, and also reduced the tumor-loading rate. The decoction also showed inhibitory effect on the growth and metastasis of Lewis pulmonary cancer in the implanted mice. The experiment also showed that CML could promote transformation of lymphocytes in the spleen and the activity of phagocytes in the abdomen, and inhibited growth of the cultivated throat cancer cells or the formation of cancer cell colonies. The action of CML is similar to that of CSS in nature and intensity of action. |
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| Keywords: | CML CSS S180 Lewis pulmonary cancer Phagocytes |
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