| 萘哌地尔治疗女性尿道综合征的临床体会 |
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| 引用本文： | 黄后宝,姜书传,董昌斌,钱立新. 萘哌地尔治疗女性尿道综合征的临床体会[J]. 医学研究生学报, 2005, 18(9): 821-823 |
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| 作者姓名： | 黄后宝 姜书传 董昌斌 钱立新 |
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| 作者单位： | 1. 南京医科大学第一附属医院泌尿外科,江苏,南京,210029
2. 皖南医学院附属弋矶山医院泌尿外科,安徽,芜糊,241001 |
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| 摘 要： | 目的：探讨萘哌地尔（Naftopidil）治疗女性尿道综合征的有效性和安全性。方法：38例患者采用自身对照试验，洗脱期1周，治疗期4周，应用萘哌地尔片25mg，每晚口服。以尿道综合征症状评分（FUSS）为主要疗效指标，以生活质量评分（QOL）为次要观察指标。结果：治疗2周后患者症状开始好转，4周后疗效显著。治疗前后的FUSS、QOL相比较，差异显示均有统计学意义（P〈0．01及P〈0．05），总有效率为76．31％。结论：萘哌地尔治疗女性尿道综合征有效、安全。
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| 关 键 词： | 萘哌地尔 尿道综合征 有效性 安全性 |
| 文章编号： | 1008-8199（2005）09-0821-03 |
| 收稿时间： | 2005-04-03 |
| 修稿时间： | 2005-06-24 |
The efficacy of naftopidil in treatment of female urethral syndrome |
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| HUANG Hou-bao,JIANG Shu-chuan,DONG Chang-bin,QIAN Li-xin. The efficacy of naftopidil in treatment of female urethral syndrome[J]. Bulletin of Medical Postgraduate, 2005, 18(9): 821-823 |
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| Authors: | HUANG Hou-bao JIANG Shu-chuan DONG Chang-bin QIAN Li-xin |
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| Abstract: | Objective: To evaluate the efficacy and safety of Naftopidil on patients with female urethral syndrome (FUS). Methods: Self-controlled clinical trial was performed in patients with FUS. Thirty-eight patients were treated with naftopidil tablet 25mg/po/qn for 4 weeks after one-week washout period. The effects were evaluated mainly by female urethral syndrome score (FUSS) and quality of life (QOL). Results: FUSS began to decrease after 2 (week's) administration and decreased significantly after 4 weeks' treatment. It had statistically significant difference of FUSS and QOL after treatment compared with control (P<0.01 or P<0.05). The total effective rate was 76.31%. Conclusion:Naftopidil was safe and effective in treating FUS. |
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| Keywords: | Naftopidil Female urethral syndrome Efficacy Safety |
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