| 40例寻常型银屑病患者血清锌与超氧化物歧化酶检测 |
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| 引用本文： | 雷田兵,陈德宇,罗模桂.40例寻常型银屑病患者血清锌与超氧化物歧化酶检测[J].岭南皮肤性病科杂志,2008,15(2):70-73. |
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| 作者姓名： | 雷田兵 陈德宇 罗模桂 |
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| 作者单位： | 1. 四川省自贡市第四人民医院皮肤科,四川,自贡,643000
2. 泸州医学院附属医院皮肤科,四川,泸州646000 |
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| 摘 要： | 目的:观察血清锌与超氧化物歧化酶(SOD)对寻常型银屑病的影响,探讨银屑病的病因和发病机制。方法:对40例银屑病患者各期行PASI评分;银屑病患者各期和对照组采用原子分光光度法检测血清锌值,用黄嘌呤氧化酶法检测SOD。结果:银屑病患者各期血清锌和SOD较对照组显著降低(P<0.01);银屑病患者各期SOD与PASI评分呈负相关(P<0.01),血清锌与SOD呈负相关(P<0.01),但对照组血清锌与SOD呈负相关(P<0.01)。结论:银屑病患者存在着血清锌和SOD的降低;缺锌是银屑病患者SOD降低的主要原因。
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| 关 键 词： | 寻常型银屑病 PASI评分 锌 超氧化物歧化酶 |
| 文章编号： | 1009-8968(2008)02-0070-04 |
| 修稿时间： | 2007年12月6日 |
The detection and analysis of Serum Zn and SOD in 40 patients with psoriasis vulgaris |
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| LEI Tian-bing,CHEN De-yu,LUO Mo-gui.The detection and analysis of Serum Zn and SOD in 40 patients with psoriasis vulgaris[J].Southern China Journal of Dermato-Venereology,2008,15(2):70-73. |
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| Authors: | LEI Tian-bing CHEN De-yu LUO Mo-gui |
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| Institution: | LEI Tian-bing; CHEN De-yu; LUO Mo-gui(The department of dermatology; The 4th people s hospital of Zigong; Zigong 643000; China); |
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| Abstract: | Objective:To observe the relationship between serum Zn and SOD and the activity of psoriasis,and investigate the pathogenesis of psoriasis. Methods:40 cases of psoriasis vulgaris was scored with PASI,serum Zn level and SOD level were measured for the 40 cases and healthy people.Results:Compared with the healthy people,the level of serum Zn and SOD in different stage of psoriasis was obviously low(P<0.01);The level of serum SOD and serum Zn was negatively correlated(P<0.01)with the scores of PASI;In control group,serum Zn and SOD was negatively correlated(P<0.01).Conclusion:the level of serum Zn and SOD decreased in psoriasis patients;the shortage of Zn might be the reason for SOD's decrease. |
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| Keywords: | Psoriasis vulgaris Psoriasis area and severity index Zinc Superoxide dismutase |
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