| 巨噬细胞对结核分枝杆菌免疫反应的研究进展 |
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| 引用本文： | 孟繁荣,谢贝,刘志辉.巨噬细胞对结核分枝杆菌免疫反应的研究进展[J].现代医院,2013(12):10-13. |
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| 作者姓名： | 孟繁荣 谢贝 刘志辉 |
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| 作者单位： | 广州市胸科医院肺部疾病研究所,广东广州510095 |
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| 基金项目： | 基金项目：广州市卫生局医药卫生科技项目（编号：201102A213148） |
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| 摘 要： | 巨噬细胞是结核分枝杆菌感染人体后的主要寄居场所。细胞介导的免疫反应是机体抗结核分枝杆菌的主要免疫保护机制，巨噬细胞通过吞噬、自噬、抗原提呈、产生多种细胞因子、自由基。以及细胞凋亡等多种途径杀灭结核分枝杆菌。笔者就巨噬细胞对结核分枝杆菌的免疫反应机制做一综述。
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| 关 键 词： | 巨噬细胞 结核分枝杆菌 免疫反应 |
RESEARCH PROGRESS ON IMMUNE RESPONSE OF MACROPHAGE TO MYCOBACTE- RIUM TUBERCULOSIS |
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| MENG Fanrong,XIE Bei,LIU Zhihui.RESEARCH PROGRESS ON IMMUNE RESPONSE OF MACROPHAGE TO MYCOBACTE- RIUM TUBERCULOSIS[J].Modern Hospital,2013(12):10-13. |
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| Authors: | MENG Fanrong XIE Bei LIU Zhihui |
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| Institution: | ( The Pulmonary Disease Research Institute of Guangzhou Chest Hospital, Guangzhou City, Guangdong Province 510095 PRC) |
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| Abstract: | Macrophage is the main host cell of Mycobacterium tuberculosis in the body. Cell mediated im- mune response is the main immune protection mechanism in body anti - Mycobaeterium tuberculosis. Macrophage kills Mycobacterium tuberculosis through phagocytosis, autophagy, presenting antigens, producing a variety of cyto- kines and free radicals, apoptosis and many other ways. This article reviews the research progress on immune re- sponse of macrophage to Mycobacterium tuberculosis. |
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| Keywords: | Macrophage Mycobacterium tuberculosis Immune response |
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