脊柱结核抗结核药物化学治疗的思考

脊柱结核是最常见的肺外结核之一,随着现代影像学、实验室诊断技术的不断进步,脊柱结核的确诊率逐年增高。脊柱结核的治疗原则以抗结核药物化学治疗为根本,营养支持、手术治疗为辅助。作者就脊柱结核化学治疗的特点、时机、方案制定、药物选择、疗程、局部化学治疗、停药指征等进行阐述,为临床治疗提供参考。

The thinking of chemotherapy for patients with spinal tuberculosis

Spinal tuberculosis is one of the most common types of extra-pulmonary tuberculosis. With the progress of the modern imaging and laboratory diagnostic techniques, the confirmed diagnosis rate of spinal tuberculosis is increased year by year. The principles of the spinal tuberculosis treatment are as follows: anti-tuberculosis chemotherapy is the basic method of treatment; nutrition support and surgical treatment are the supplemental me-thods. In order to provide a reference for the clinical treatment of the patients with spinal tuberculosis, in this study, we described the characteristics of the anti-tuberculosis chemotherapy to the patients with spinal tuberculosis, time of the chemotherapy initiation, design of the treatment regimens selection of the anti-tuberculosis drugs and the treatment duration, as well as the local anti-tuberculosis chemotherapy, indications for stopping anti-tuberculosis chemotherapy.