| 视网膜色素上皮移植细胞超微结构的观察 |
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| 引用本文： | Li G,Wu L,Gao R,Wu D. 视网膜色素上皮移植细胞超微结构的观察[J]. 中华眼科杂志, 1999, 0(1): 50-51,I002 |
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| 作者姓名： | Li G Wu L Gao R Wu D |
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| 作者单位： | [1]第一军医大学附属南方医院眼科 [2]中山医科大学中山眼科中心 |
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| 摘 要： | 目的 观察视网膜色素上皮移植细胞的超微结构,为临床应用提供实验基础。方法 取有色兔眼球后段,去除视网膜的神经上皮层,获得视网膜色素上皮细胞作为移植的供体细胞。以１０只无色兔为移植的受体,内路法将供体色素上皮细胞移植到视网膜下腔,电镜观察移植细胞的超微结构。结果 移植的１０只眼,细胞成功移植到视网膜下腔,可见移植细胞粘附于受体的Ｂｒｕｃｈ膜并形成基底内褶,细胞间紧密连接,细胞内可见吞噬体。结论 内路
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| 关 键 词： | 移植 视网膜色素上皮 超微结构 |
The study of ultrastructure of retinal pigment epithelium of transplantation |
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| Li G,Wu L,Gao R,Wu D. The study of ultrastructure of retinal pigment epithelium of transplantation[J]. Chinese Journal of Ophthalmology, 1999, 0(1): 50-51,I002 |
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| Authors: | Li G Wu L Gao R Wu D |
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| Affiliation: | Department of Ophthalmology, The First Military University of Medical Sciences, Guangzhou 510515. |
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| Abstract: | OBJECTIVE: To investigate the ultrastructure of retinal pigment epithelium (RPE) for the base of clinical application. METHODS: Pigmented rabbit RPE was transplanted to the subretinal space of 10 unpigmented rabbits by internal route. The ultrastructure of transplanted RPE cells were observed by electron microscopy. RESULTS: The transplantation of RPE was successful. It was shown that the transplanted cells had polarity and attached to Bruch's membrane to form basal infoldings, and the relationships between transplanted cells and the host photoreceptors were also seen. CONCLUSIONS: The internal approach is a practical and useful method for transplantation of RPE. The transplanted RPE can vitalize, perform metabolism and form some normal ultrastructure. |
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| Keywords: | Retinal pigment epithelium Transplantation |
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