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东菱精纯克栓酶治疗TIAs的TCD观察
引用本文:赵玲,黄友荣,马磊,陈传玉,封飞.东菱精纯克栓酶治疗TIAs的TCD观察[J].实用全科医学,2005,3(4):305-306.
作者姓名:赵玲  黄友荣  马磊  陈传玉  封飞
作者单位:山东省滕州市中心人民医院 277500(赵玲,黄友荣,马磊,陈传玉),山东省滕州市中心人民医院 277500(封飞)
基金项目:枣庄市科技局资助科研课题,2004055
摘    要:目的应用经颅多普勒(TCD)技术观察东菱精纯克栓酶(DF-521)治疗频发的短暂性脑缺血发作(TIAs)的疗效。方法100例TIAs住院患者随机分为DF-521治疗组(50例)和川芎嗪-阿司匹林对照组(50例)。应用TCD技术,分别观察两组血流动力学变化,并进行对比研究。结果治疗组的血流动力学变化明显优于对照组(P<0.01),停止发作时间早于对照组。结论DF-521治疗TIAs起效快、效果好、安全性高。应用TCD技术,为指导临床和评估疗效提供了有力的依据。

关 键 词:东菱精纯克栓酶  TIAs  血流动力学变化  短暂性脑缺血发作  TCD技术  DF-521  经颅多普勒  521治疗  对照组  阿司匹林  住院患者  对比研究  发作时间  治疗组  川芎嗪  安全性  疗效
修稿时间:2004年11月20

Observation on Batroxobin Injection for Treatment of Transient Ischemic Attack by Transcranial Doppler Technology
ZHAO Ling,HUANG Yourong,MA Lei,et al..Observation on Batroxobin Injection for Treatment of Transient Ischemic Attack by Transcranial Doppler Technology[J].Applied Journal Of General Practice,2005,3(4):305-306.
Authors:ZHAO Ling  HUANG Yourong  MA Lei  
Institution:ZHAO Ling,HUANG Yourong,MA Lei,et al .Central Hospital of Tengzhou,Shangdong 277500,China
Abstract:Objective To investigate the effects of Batroxobin in the treatment of transient ischemia attacks( TIAs ) by transcranial Doppler technology. Methods One hundred cases with TIAs were randomly divided into Batroxobin injection group(n=50) and Ligustrazine injection-Aspirin group(n=50, control). The changes of hemodynamics were observed before and after treatment. Results The changes of hemodynamics in Batroxobin group were superior to that in control group (P<0.01). The symptoms of experimental group disappeared earlier than the control group. Conclusions Batroxobin is an effective and safe medicament for TIAs. The technology of TCD can provide a new instruction for clinical selection of reasonable treatment and the evaluation of effect.
Keywords:Batroxobin injection  Transient cerebral ischemia attack  Transcranial Doppler  Hemodynamics
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