^99m^Tc—MIBI显像,^131I—WBS和HTG测定对分化型甲状腺癌^13 …

为对＾９９ｍＴｃ－ＭＩＢＩ显像、＾１３１Ｉ－ＷＢＳ和ＨＴＧ测定，在分化型甲状腺癌＾１３１Ｉ治疗后随访中的价值进行对比研究，对５３例分化型甲状腺癌患者依次行ＨＴＧ测定、＾９９Ｔｃ－ＭＩＢＩ显像和＾１３１Ｉ－ＷＢＳ。结果：＾９９ｍＴｃ－ＭＩＢＩ显像的灵敏度、特异性和准确性分别为８６．３６％、８７．１０％、８６．７９％；ＨＴＧ测定和＾１３１Ｉ－ＷＢＳ灵敏度分别为６８．１８％和６３．３４％，特异性为１００

Clinical value of 99mTc-MIBI imaging, 131I whole body scan and HTG determination for the follow-up of patients with differentiated thyroid carcinoma after 131I therapy]

The purpose of this study was to make a comparative evaluation of 99mTc-MIBI imaging, 131I whole body scan and HTG determination in use for the follow-up of patients with differentiated thyroid carcinoma (DTC) after 131I therapy. Fifty-three patients with DTC had undergone surgical treatment and 131I ablation. Clinical examinations showed that 22 of them had metastases or recurrences. In the follow-up of all the patients, the HTG determination, the 99mTc-MIBI imaging and the 131I-WBS were performed in sequence after the discontinuance of the administration of thyroxin for 4-6 weeks. The results showed that the sensitivity, specificity and accuracy of 99mTc-MIBI imaging were 86.36%, 87.10% and 86.79% respectively; those for HTG were 68.18%, 100% and 86.79% and those for 131I-WBS were 63.64%, 100% and 84.91% respectively. The total sensitivity of the three examinations was 100%; the total specificity and total accuracy were 87.10% and 92.45% respectively. The data of this study suggest that 99mTc-MIBI imaging is a highly sensitive method and the combined use of the three examinations can improve the sensitivity and accuracy of diagnosis for patients with DTC.