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正常青年人脑组织不同回波时间磁共振波谱分析
引用本文:张辉,李军东,王效春,吴江,毛小峰,苏晋生. 正常青年人脑组织不同回波时间磁共振波谱分析[J]. 中国药物与临床, 2005, 5(11): 825-827
作者姓名:张辉  李军东  王效春  吴江  毛小峰  苏晋生
作者单位:1. 山西医科大学第一医院放射科,030001
2. 太原市中心医院影像科
摘    要:目的探讨不同回波时间(TE)对正常青年人脑组织代谢物含量的影响。方法选择23名健康青年志愿者,进行二维1H-磁共振波谱(MRS)检查,TE分别为135 ms和270 ms,对比分析N-乙酰门冬氨酸(NAA)/肌酐(Cr)、胆碱(Cho)/Cr及NAA/Cho比值。结果在正常青年人右侧基底节区,TE=135 ms,NAA/Cr、Cho/Cr和NAA/Cho比值分别为2.1±0.6、1.2±0.3和1.7±0.4;TE=270 ms,NAA/Cr、Cho/Cr和NAA/Cho比值分别为2.8±0.8、1.4±0.4和2.0±0.5。TE=135 ms组与TE=270 ms组比较,NAA/Cr、Cho/Cr及NAA/Cho比值差异均有统计学意义(P<0.05)。男性组与女性组比较,NAA/Cr、Cho/Cr及NAA/Cho比值差异均无统计学意义(P>0.05)。结论TE=270 ms所测量的NAA/Cr、Cho/Cr及NAA/Cho比值均高于TE=135 ms所测量的比值,性别不是影响正常青年人脑组织代谢物含量的因素。

关 键 词:磁共振波谱学  诊断,鉴别  性别因素  回波时间  正常青年人
收稿时间:2005-07-04
修稿时间:2005-07-04

Analysis of 1H-magnetic resonance spectroscopy with different echo time in the brain of healthy young people
ZHANG Hui,LI Jun-dong,WANG Xiao-chun,WU Jiang,MAO Xiao-feng,SU Jin-sheng. Analysis of 1H-magnetic resonance spectroscopy with different echo time in the brain of healthy young people[J]. Chinese Remedies & Clinics, 2005, 5(11): 825-827
Authors:ZHANG Hui  LI Jun-dong  WANG Xiao-chun  WU Jiang  MAO Xiao-feng  SU Jin-sheng
Abstract:Objective To explore different echo times(TE) affecting metabolite content in the brain of healthy young people.Methods 2D 1H-magnetic resonance spectroscopy(MRS) was carried out in 23 healthy volunteers.The metabolite ratios of NAA/Cr,Cho/Cr and NAA/Cho were compared and analysed with 135 ms of TE and 270 ms of TE.Results The mean peak ratios of NAA/Cr,Cho/Cr and NAA/Cho in the right basal ganglia in the brain of healthy young people were 2.1±0.6,1.2±0.3 and 1.7±0.4 in 135 ms of TE;2.8±0.8,1.4±0.4 and 2.0±0.5 in 270 ms of TE.Each ratio of NAA/Cr,Cho/Cr or NAA/Cho was significantly different between TE 135 ms and TE 270 ms in the right basal ganglia in the brain of healthy young people(P<0.05).Conclusion Each ratio of NAA/Cr,Cho/Cr and NAA/Cho in TE 270 ms is higher than that in TE 135 ms.Sex has not significant effect on metabolites in the brain of healthy young people.
Keywords:Magnetic resonance spectroscopy  Diagnosis  differential  Sex factors  Echo time  Healthy young people
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