腹泻患儿粪便中轮状病毒抗原快速检测及其临床意义

目的 探讨粪便中轮状病毒抗原对临床诊断的价值。方法 以520例秋冬季腹泻患儿为研究对象,应用轮状病毒单克隆抗体检测病毒抗原的方法,测定其大便中轮状病毒抗原。结果 检出轮状病毒抗原阳性患儿315例,阳性率为60.6％。将6 mo~2 y婴幼儿组与<6 mo婴儿组、2~6 y幼儿组作比较(x2检验)P<0.05及P<0.01,表明6 mo~2 y婴幼儿为轮状病毒感染的高发期。同一年龄组男女患儿间阳性率差异无显著性(P>0.05)。结论 粪便中轮状病毒抗原检测是诊断轮状病毒肠炎较敏感的方法,对临床诊断该病提供了有价值的依据。

Clinical Study of Fecal Rotavirus Antigen Rapid Detection of Infant Diarrhea

Objective To explore the value of fecal rotavirus antigen in clinical diagnosis. Methods 520 cases of infant diarrhea in autumn and winter were tested with rotavirus monoclone antibody for detection of rotavirus antigen in their facal specimens. Results 315 cases were positive in the test. The positive rate was 60. 6%. They were compared in different groups 6 months-2 years,less than 6 months and 2-6 years group(X2). The results showed that there was higher mobility for rotavirus infection in 6 months-2 years group. There was no difference in sex in same group. Conclusion The test of fecal rotavirus antigen is the sensitive measure in the diagnosis of the rotavirus enteritis. It is valuable to the diagnosis of the disease.