243例肾穿刺活检病例的临床、病理分型及与中医证候相关性分析

目的 了解我院肾脏疾病患者的临床分型、病理分型及与中医证候的相关性.方法 对243例住院行肾穿刺活检患者的临床分型、病理分型、中医证候资料进行回顾性分析.结果 肾小球疾病(GN)241例,占99.2%;其中原发性肾小球疾病(PGN)176例占73.0%,继发性肾小球疾病(SGN)65例占27.0%.PGN中肾小球微小病变(MCD)、IgA肾病(IgAN)及系膜增生性肾小球肾炎(MsPGN)所占比例较高,分别为30.1%、22.1%、18.8%.SGN中狼疮性肾炎(LN)及乙肝病毒相关性肾炎分别占81.5%、10.8%.PGN中以本虚标实证为主,占83.5%;SGN中也以本虚标实证多见,占96.9%.结论 GN是我院肾活检病例中最常见原因,原发多于继发.PGN中MCD最常见,其次为IgAN与MsPGN;SGN中,LN是首要原因.PGN及SGN均以本虚标实证为多见.

Clinical and pathological types and their correlation to TCM syndromes in 243 cases with kidney puncture and biopsy

Objective To find out the clinical types and pathologic types, and their correlation to TCM syndromes in the patients with kidney diseases. Method The retrospective analysis was made on the materials of clinical types, pathologic types and TCM syndrome patterns in 243 in-patients with kidney puncture and biopsy. Result There were 241 cases of glomerulonephropathy (GN, 99.2 %) and among them 176 cases of primary glomerulonephropathy (PGN, 73.0 %) and 65 cases of secondary glomerulonephropathy (SGN, 27.0 %). In PGN cases minimal change glomerulopathy (MCG), IgA nephropathy (IgAN) and mesangial proliferative glomerulonephritis (MsPGN) accounted for a higher proportion (30.1 %, 22.1 % and 18.8 % respectively). In SGN cases lupus nephritis (LN) and hepatitis B virus related nephritis accounted for 81.5% and 10.8% respectively. In PGN cases the proportion of TCM syndrome pattern of root deficiency and incidental excess was 83.5 % and that in SGN cases was 96.9 %. Conclusion Glomerulonephropathy is the most common cause in the cases of kidney puncture and biopsy and PGN cases was more than SGN cases. In PGN cases MCG was more common than IgAN and MsPGN and in SGN cases LN was the chief cause. The TCM syndrome pattern in the cases of PGN and SGN was mostly the syndrome of root deficiency and incidental excess.