Description of fourteen new DRB alleles found in a stem cell donor registry |
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Authors: | Tang T F Lin Y-S Robbins F-M Li L Sintasath D Coquillard G Huang A Heine U Ng J Hartzman R J Hurley C K |
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Affiliation: | Department of Pediatrics, Georgetown University, Washington, DC, USA. |
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Abstract: | Fourteen DRB alleles, DRB1*0705, DRB1*11014, DRB1*1134, DRB1*1136, DRB1*1141, DRB1*1335, DRB1*1337, DRB1*1338, DRB1*1342, DRB1*1343, DRB1*1349, DRB1*1510, DRB3*0105, and DRB5*0103, are described. Among them, eleven are variants which differ by only one nucleotide from previously described alleles, including one silent variant (DRB1*11014). Alleles, DRB1*0705, DRB1*1335 and DRB3*0105, display unique sequence motifs that have never been observed in DRB alleles. |
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