10例原发性宫颈淋巴瘤临床分析

目的探讨宫颈淋巴瘤的发病、诊断、治疗及预后。方法临床资料回顾性分析。结果本组病例占同期宫颈恶性肿瘤的０．９％,１０例患者平均年龄４３．６岁,７例有癌肿家族史,临床症状以阴道出血和／或白带增多为主,肿瘤形态为息肉型（４例）、糜烂型（４例）和结节型（２例）。按ＦＩＧＯ分期：Ⅰｂ期８例,Ⅱｂ期１例,Ⅳ期１例。本组病例均经病理确诊,病理类型上属非霍奇金淋巴瘤（ＮＨＬ）,Ｂ细胞性,其中弥漫型裂细胞性３例,裂－无裂细胞性４例。１０例患者采用手术和化疗为主的综合治疗,随访期３～６６个月,除１例术后４１个月腋下转移外,９例无瘤生存。结论如果发现早,治疗适当,宫颈淋巴瘤疗效并非很差。

Ten-case report on primary cervical lymphoma

OBJECTIVE AND METHODS: Clinical feature, treatment and prognosis of primary cervical lymphoma: are retrospectively analysied. RESULTS: The disease is rare, comprising about 0.9% of all primary cervical malignancies. The average age was 43.6 years. Seven cases had history of familial carcinoma. The complaints: abnormal vaginal bleeding and/or vaginal discharge. The usual pattern of growth was endophytic or polypoid. By FIGO cervical cancer, staging system, there were 8/10 stage I b, 1/10 stage II b and 1/10 stage IV. Histologically all were NHL, B cell lesions(7/10) were the diffuse, cleaved or cleaved-noncleaved cell type. Combination of surgery and chemotherapy were used for 9 of these 10 patients. The follow-up period was 3-66 months. Only one patient had relapse 41 months after the treatment while, others (9/10) survived with no evidence of the disease. CONCLUSION: The prognosis is favorable if cervical lymphoma is discovered early and treated properly.