Neuropsychological assessment in multiple sclerosis: a follow-up study with magnetic resonance imaging |
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Authors: | C. Mariani E. Farina S. F. Cappa G. P. Anzola L. Faglia L. Bevilacqua R. Capra F. Mattioli L. A. Vignolo |
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Affiliation: | (1) Istituto di Clinica Neurologica, University of Milan, Via F. Sforza, 35, I-20122 Milan, Italy;(2) Clinica Neurologica, University of Brescia, Bresica, Italy;(3) Department of Neurology, Ospedale Niguarda Ca'Granda, Milan, Italy |
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Abstract: | Summary Nineteen moderately impaired patients with clinically definite multiple sclerosis and an initially relapsing-remitting course were included in a neuropsychological and magnetic resonance imaging (MRI) follow-up study. The average test/re-test interval was about 2 years. The neuropsychological findings were indicative of a very mild overall impairment; the patients, as a group, showed no evidence of cognitive deterioration in the follow-up period. A numerical estimation of the severity of cerebral demyelination shown by MRI did not indicate a significant change. No correlation between cognitive performance variations and MRI changes was found. |
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Keywords: | Multiple sclerosis Magnetic resonance imaging Neuropsychological assessment |
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