| 均匀实验设计在4-羟基二苯酮制备工艺中应用 |
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| 引用本文： | 陈琳珏,杨文泉. 均匀实验设计在4-羟基二苯酮制备工艺中应用[J]. 黑龙江医药科学, 2004, 27(1): 24-25 |
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| 作者姓名： | 陈琳珏 杨文泉 |
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| 作者单位： | 佳木斯大学理学院,黑龙江,佳木斯,154007;佳木斯大学理学院,黑龙江,佳木斯,154007 |
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| 摘 要： | 目的：优化4-羟基二苯酮制备工艺；方法：应用均匀实验设计方法；结果：与正交设计相比，大幅度减少试验次数，收率由62％提高到83％，产品质量也有较大改善；结论：本方法用于合成工艺优化切实可行。
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| 关 键 词： | 均匀实验设计 4-羟基二笨酮 制备工艺 |
| 文章编号： | 1008-0104(2004)01-0024-01 |
| 修稿时间： | 2003-11-24 |
Application of the well-distributed experiment design in the preparation technology for 4-trihydro-two-benzophenone |
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| CHEN Lin-jue,YANG Wen-quan. Application of the well-distributed experiment design in the preparation technology for 4-trihydro-two-benzophenone[J]. Heilongjiang Medicine and Pharmacy, 2004, 27(1): 24-25 |
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| Authors: | CHEN Lin-jue YANG Wen-quan |
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| Abstract: | Objective: To optimizate the preparation technology for 4-trihydro-two-benzophenone.Methods:The well-distributed experiment design was used.Results:Compared with orthogonal test,the experimental time was significantly decreased,but the average recovery was raised from 62% to 83% and the product quality was improved.Conclusion:This technology can be used to optimizate its synthetic process. |
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| Keywords: | well-distributed experiment design 4-trihydro-two-benzophenone the preparing technics |
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