| 兰州地区献血员及静脉毒瘾者血清中TT病毒核酸检测及意义 |
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| 引用本文： | 刘旺国,聂青和,李爱月,焦建中,韩梅英. 兰州地区献血员及静脉毒瘾者血清中TT病毒核酸检测及意义[J]. 实用肝脏病杂志, 1999, 0(3) |
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| 作者姓名： | 刘旺国 聂青和 李爱月 焦建中 韩梅英 |
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| 作者单位： | 解放军第一医院传染病科，第四军医大学唐都医院传染病科，解放军第一医院传染病科，解放军第一医院传染病科，解放军第一医院传染病科 730030 兰州市，730030 兰州市，730030 兰州市，730030 兰州市 |
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| 摘 要： | 目的 研究兰州地区献血员及静脉毒瘾者中TT病毒(TTV)的感染状况。方法 利用套式PCR技术检测献血员及静脉毒瘾者血清中TTV DNA。结果 献血员中TTV DNA检出率为7.5％(9/120)。静脉毒瘾者中TTVDNA枪出牢为26.8％(15/56),明显高于献血员组,结论 首次报道兰州地区存在TTV感染。静脉毒瘾者为了TTV感染的高危人群,其致病性较弱。关于TTV的病原学、流行病学、病理学及临床意义等有待进一步探索。
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| 关 键 词： | 输血传播病毒 套式多聚酶链反应 献血员 静脉毒瘾者 |
DETECTION OF TRANSFUSION-TRANSMITTED VIRUS (TTV) DNA IN BLOOD DONORS AND INTRAVENOUS DRUG-ABUSERS IN LANZHOU |
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| Liu Wangguo,Nie Qinghe,Li Aiyue,et al.. DETECTION OF TRANSFUSION-TRANSMITTED VIRUS (TTV) DNA IN BLOOD DONORS AND INTRAVENOUS DRUG-ABUSERS IN LANZHOU[J]. Journal of Clinical Hepatology, 1999, 0(3) |
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| Authors: | Liu Wangguo Nie Qinghe Li Aiyue et al. |
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| Affiliation: | Liu Wangguo,Nie Qinghe,Li Aiyue,et al. The First Hospital of PLA,Lanzhou,730030 |
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| Abstract: | Objective To study the infection rate of transfusion-transmitted virus (TTV) among blooddonors and intravenous drug-abusers in Lanzhou. Methods Nested-PCR(nPCR) was performed for detecting TTV DNA in sera of blood donors and intraverous drug-abusers. Results TTV DNA was detected in 9/120(7. 5% ) sera of blood donors and in 15/56(26.8%) of intraverous drug-abusers. Conclusions The results of this study for the first time confirmed the presence of TTV infection in Lanzhou. The intraverous drug-abusers is the high risk population for TTV infection. Further study should be done to explore TTV's etology,epidemiology, pathology and clinical significance. |
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| Keywords: | Transfusion -Transmitted Virus Nested-PCR Blood Donor Intravenous Drug-abuser |
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