复方血栓通胶囊对早期糖尿病肾病患者血清炎性指标的影响

目的探讨复方血栓通胶囊对早期糖尿病肾病患者血清CRP、TNF-α、IL-6的影响。方法将血压正常的90例早期糖尿病肾病患者随机分为对照组和治疗组。对照组予以控制血糖、糖尿病教育等常规治疗；治疗纽在常规治疗的基础上加用复方血栓通胶囊3粒，每日3次，均治疗12周。观察治疗前后二组患者血清CRP、TNF-α、IL-6及尿微量白蛋白的变化。结果治疗12周后，治疗组与治疗前相比尿微量白蛋白及血清CRP、TNF-α、IL-6均较前明显降低；且明显优于对照组。结论复方血栓通胶囊能明显降低早期糖尿病肾病患者尿微量白蛋白及血清CRP、TNF-α、IL-6水平，对早期糖尿病肾病具有治疗作用。

Effect of Fufang Xueshuantong Capsule on Serum Inflammatory Indicators of Early Diabetic Nephropathy Patients

[Abstract]Objective To observe the influence of Fufang Xueshuantong capsule on serum CRP, TNF-α. IL-6 of Early Diabetic Nephropathy Patients. Methods Ninety patients who Blood pressure is in the normal range were divided into control group and treatment group,All of them were given Control blood glucose,diabetic education Conventional treatment and so on. While those in treatment group,besides of treatment as control group,were given Fufang Xueshuantong capsule,All treatment course were 12 weeks.Then the urinary microalbumin and the serum CRP. TNF-α. IL-6 were measured before and after treatment.Results After 12 weeks treatment,the level of UAER,CRP TNF-α,IL-6 of the two groups were lower than those before,but the treatment group decreased significantly. Conclusion Fufang Xueshuantong capsule can decrease the urinary microalbumin and the serum CRP. TNF-α, IL-6 of early diabetic nephropathy patients,and has therapeutical effect to them.