| 牛大力祛痰、镇咳和平喘作用的实验研究 |
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| 引用本文： | 刘丹丹,唐立海,王艳,肖细姬,刘亮锋,叶木荣. 牛大力祛痰、镇咳和平喘作用的实验研究[J]. 广州中医药大学学报, 2009, 26(3) |
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| 作者姓名： | 刘丹丹 唐立海 王艳 肖细姬 刘亮锋 叶木荣 |
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| 作者单位： | 广州中医药大学中药学院,广东广州,510405;山西中医学院,山西太原,030006 |
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| 摘 要： | [目的]观察牛大力的祛疫、镇咳及平喘作用.[方法]通过小鼠气管酚红法、家鸽纤毛运动实验、小鼠浓氨水引咳法、豚鼠枸橼酸引咳法及豚鼠组胺-乙酰胆碱超声雾化法观察牛大力的祛痰镇咳平喘作用.[结果]牛大力能显著增加小鼠气管酚红排泌量,促进家鸽气管内墨汁运动,减少氨水引发小鼠和枸橼酸引发豚鼠咳嗽反应的次数,延长咳嗽潜伏期,对抗组胺-乙酰胆碱引起的豚鼠支气管哮喘(均P＜0.05或P＜0.01).[结论]牛大力具有一定的祛痰、镇咳及平喘作用.
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| 关 键 词： | 牛大力/药理学 慢性支气管炎/中药疗法 疾病模型 动物 小鼠 豚鼠 家鸽 |
Experimental Study on the Expectorant,Antitussive and Antiasthmatic Effects of Radix Millettiae Speciosae |
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| LIU Dandan,TANG Lihai,WANG Yan,XIAO Xiji,LIU Liangfeng,YE Murong. Experimental Study on the Expectorant,Antitussive and Antiasthmatic Effects of Radix Millettiae Speciosae[J]. Journal of Guangzhou University of Traditional Chinese Medicine, 2009, 26(3) |
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| Authors: | LIU Dandan TANG Lihai WANG Yan XIAO Xiji LIU Liangfeng YE Murong |
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| Affiliation: | 1. School of Chinese Herbal Medicine;Guangzhou University of TCM;Guangzhou 510405 Guangdong;China;2.Shanxi College of TCM;Taiyuan 030006 Shanxi;China |
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| Abstract: | Objective To observe the expectorant,antitussive and antiasthmatic effects of Radix Millettiae Speciosae (RMS).Methods Expectorant effects were evaluated by measuring the excretion of phenol red in mice trachea and by observing the pigeon tracheal ciliary movement.Antitussive effects were observed through mice cough test induced by ammonia water steaming and through guinea pigs cough test induced by citric acid.Antiasthmatic actions in guinea pigs were observed by histamine and acetylcholine ultrasonic atom... |
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| Keywords: | RADIX MILLETTIAE SPECIOSAE/pharmacology CHRONIC BRONCHITIS/TCD therapy DISEASE MODELS ANIMAL MICE GUINEA PIGS PIGEONS |
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