Skin prick test reactions to brewer's yeast (Saccharomyces cerevisiae) in adult atopic dermatitis patients |
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Authors: | O. Kortekangas-Savolainen K. Lammintausta K. Kalimo |
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Affiliation: | Department of Dermatology, University of Turku, Turku, Finland |
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Abstract: | The sensitizing capacity of brewer's yeast ( Saccharomyces cerevisiae ) was studied with the skin prick test method in 449 subjects, including 226 atopic dermatitis (AD) patients, 50 patients with allergic rhinitis (AR) and/or asthma (A), and 173 nonatopic controls. A positive SPT reaction (≥++) was seen in 94% of patients with severe AD, in 76% with moderate AD, and in 25% with mild AD or no history of AD. Patients with AR and/or A and nonatopic controls displayed a positive reaction in only 8 and 2% of cases, respectively. There was also a parallel skin prick test reactivity with other yeasts including Pityrosporum ovale and Candida albicans , suggesting cross-reactivity. Parallel skin reactivity was observed also with molds and animal dander but not with pollen or house-dust mite. A significant correlation was also found between total serum IgE level and skin prick test (SPT) results with S. cerevisiae . |
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Keywords: | atopic dermatitis baker's yeast skin prick test yeast allergy |
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