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Clinical and Flow Cytometric Analyses of Renal Cell Carcinomas with Reference to Incidental or Non-incidental Detection |
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| Authors: | Sasaki, Yukihiro Homma, Yukio Hosaka, Yoshio Tajima, Atsushi Aso, Yoshio |
| Affiliation: | 1 Department of Urology, Faculty of Medicine, the University of Tokya Tokyo 2 Department of Urology Division, Tokyo Teishin Hospital Tokyo 3 Department of Urology, Branch Hospital, the University of Tokyo Tokyo |
| Abstract: | In recent years renal cell carcinomas have been diagnosed asincidental findings. The tumors are usually associated withlow stage and good prognosis. To find out if they might havea different malignant potential from suspected tumors, we retrospectivelycompared 56 cases of incidentally detected tumors with 84 casesof suspected tumors, with regard to tumor stage, nuclear grade,tumor size and DNA ploidy pattern as evaluated by flow cytometry.The incidentally detected tumors were lower in stage (P<0.01),smaller in size (P<0.01) and higher in probability of survival(P<0.02) than the suspected tumors, as other studies havereported. Meanwhile, there was no difference in nuclear grade,DNA ploidy pattern and survival in stage I tumors between thetwo groups of renal cancers. The results suggest that the betterprognosis in incidental renal cancer might be due to early detectionrather than lower malignant potential of this specific typeof renal cancer. |
| Keywords: | Renal cell carcinoma Incidental cancer Flow cytometry |
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