| 中药缓控释微丸制剂的研究进展 |
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| 引用本文： | 陈丽华,冯怡 徐德生.中药缓控释微丸制剂的研究进展[J].中国中药杂志,2007,32(6):472-475. |
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| 作者姓名： | 陈丽华 冯怡 徐德生 |
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| 作者单位： | 上海中医药大学,科技中心,上海,201203 |
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| 摘 要： | 微丸作为一种多单元释药系统,具有流动性好,释药稳定、可靠、均匀等特点。随着现代制备工艺的逐渐成熟及辅料的发展,微丸在缓控释制剂中的应用备受瞩目。作者对中药缓控释微丸制剂释药机制、制备方法、辅料及其体内过程等方面的研究进行了综述,旨在为研究开发中药口服缓控释制剂提供思路和方法。
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| 关 键 词： | 中药缓控释微丸 制备 辅料 体内过程 |
| 文章编号： | 1001-5302（2007）06-0472-04 |
| 收稿时间： | 2006-04-28 |
| 修稿时间： | 2006-04-28 |
Advances of sustained/controlled release pellets in traditional Chinese medicine |
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| CHEN Li-hua; FENG Yi; XU De-sheng.Advances of sustained/controlled release pellets in traditional Chinese medicine[J].China Journal of Chinese Materia Medica,2007,32(6):472-475. |
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| Authors: | CHEN Li-hua; FENG Yi; XU De-sheng |
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| Institution: | Center of Science and Technology, Shanghai University of Treditional Chinese Medicine, Shanghai 201203, China |
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| Abstract: | Pellets are multiple-unit drug delivery system, which have good fluidity, release stability and uniformity. With preparation techniques and excipient materials gradually established, pellets play an important part in the development of sustained/controlled release drug delivery system. The recent advances in pellets including the release mechanism, preparation methods, excipients and the characteristics in vivo for the sustained/controlled release pellets in traditional Chinese medicine (TCM) were reviewed in order to provide the strategies and rational methods for further investigations and applications. |
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| Keywords: | sustained/controlled release pellets in traditional Chinese medicine preparation excipents in vivo evaluation |
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