| 肝细胞肝癌中血管内皮生长因子及nm23-H1蛋白的表达 |
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| 引用本文： | 赵爱志,窦科峰,李开宗,付由池.肝细胞肝癌中血管内皮生长因子及nm23-H1蛋白的表达[J].第四军医大学学报,2000,21(11):1336-1337. |
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| 作者姓名： | 赵爱志 窦科峰 李开宗 付由池 |
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| 作者单位： | 第四军医大学西京医院肝胆外科,陕西,西安,710033 |
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| 摘 要： | 目的 探讨肝细胞肝癌中与肿瘤转移相关的血管内皮生长因子（ｖａｓｕｃｌａｒ ｅｎｄｏｔｈｅｌｉａｌ ｇｒｏｗｔｈ ｆａｃｔｏｒ，ＶＥＧＦ），ｎｍ２３－Ｈ１表达上的关系。方法 用免疫组化及图像分析的方法研究了４５例肝癌石蜡标本切片的ＶＥＧＦ，ｎｍ２３－Ｈ１的表达，进而探讨了ＶＥＧＦ的表达与ｎｍ２３－Ｈ１之间的关系。结果 ＶＥＧＦ及ｎｍ２３－Ｈ１与肝癌的转移均显相关，而二之间无相关性。结论 ＶＥＧＦ
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| 关 键 词： | 肝细胞肝癌 血管内皮生长因子nm23－H1 肿瘤转移 |
| 修稿时间： | : |
Expressions of vascular endothelial growth factor and nm23-H1 in hepatocellular carcinoma |
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| ZHAO Ai-Zhi,DOU Ke-Feng,LI Kai-Zong,FU You-Chi.Expressions of vascular endothelial growth factor and nm23-H1 in hepatocellular carcinoma[J].Journal of the Fourth Military Medical University,2000,21(11):1336-1337. |
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| Authors: | ZHAO Ai-Zhi DOU Ke-Feng LI Kai-Zong FU You-Chi |
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| Abstract: | AIM To investigate the relationship between the expressions of vascular endothelial growth factor (VEGF) and nm23 H1 in hepatocellular carcinoma, both of which were related to the metastasis of the tumor. METHODS With immunohistochemistry and image analysis, 45 cases of praffin embeded slides with hepatocellular carcinoma (HCC) were investigated for the relationship between the expressions of VEGF and nm23 H1. RESULTS Both VEGF and nm23 H1 were significantly related to the metastasis of HCC, but no connection was found between themselves. CONCLUSION VEGF and nm23 H1 may act on the metastasis of HCC in independent ways. |
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| Keywords: | hepatocellular carcinoma vascular endothelial growth factor nm23 H1 metastasis |
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