组织粘合剂在翼状胬肉切除联合羊膜移植术中的应用

目的:观察与探讨组织粘合剂在翼状胬肉切除联合羊膜移植术中的应用的方式方法及临床效果。方法:这是一前瞻性随机对照临床试验。将27例接受翼状胬肉切除联合羊膜移植术的患者随机分成两组:组织粘合剂组:15只眼(13例)用组织粘合剂(医用吻合胶OB)贴羊膜;缝线组:17只眼(14例)用缝线固定植片。比较两组手术时间,术后症状,体征等。应用SPSS11.0统计软件对实验结果进行相应统计学分析。结果:组织粘合剂组平均手术时间15.8min,比缝线组(23.7min)明显缩短,P<0.05。组织粘合剂组术后症状较缝线组轻,其中痛觉VAS评分明显偏低,P<0.05。羊膜植片较缝线组贴敷。其余两组无明显差异。结论:在翼状胬肉切除联合羊膜移植术中使用组织粘合剂代替缝线可明显缩短手术时间,改善术后症状。方法简便、安全、有效。

The Use of Cyanoacrylate Tissue Adhesive in the Pterygium Excisions with Amniotic Membrane Transplantation

PURPOSE: To find the proper way to use the cyanoacrylate tissue adhesive (CTA) in the pterygium excisions with amniotic membrane transplantation and To evaluate the therapeutic effects of it. METHOD: A prospective randomized clinical trial was carried out in 27 patients (32 eyes) who would have pterygium excision. They were divided into 2 groups randomly: 15 eyes in the CTA group, 17 eyes in the suture group. We evaluate the benefits of them with the respect to surgery time and postoperative sighs and symptoms. RESULTS: Average surgery time was 15.8 minutes for CTA group and 23.7 minutes for sutures, P < 0.05. The postoperative sighs were much more light in CTA group. The average pain was significantly lower when CTA had been used, P < 0.05. And the amniotic membrane was attached much better. The two groups have no significant difference in the other aspects. CONCLUSION: Using CTA instead of sutures when attaching the amniotic membrane in pterygium surgery shortens surgery time significantly and improve the postoperative sighs and symptoms. It's easy, safe and effective.