胰岛素抵抗与冠心病关系探讨

本文分析３０名正常人和３０名冠心病（ＣＨＤ）患者血清胰岛素（ＩＳ）释放水平、血脂、血压及它们之间的相关关系，发ＣＨＤ者均存在不同程度高胰岛素血症和胰岛素抵抗（ＩＳＲ），血压相对较高，低密度脂蛋白胆固醇（ＬＤＬ─Ｃ）增高，高密度脂蛋白胆固醇（ＨＤＬ─Ｃ）减低。多元回归分析显示，ＩＳＲ是ＣＨＤ的独立危险因素之一。调节饮食和增加体力活动，减少体重指数（ＢＭＩ），降低机体对胰岛素的抵抗是预防和治疗ＣＨＤ的重要手段之一。

study on the relation between insulin resistance and CHD

In this article,we analvsed the serum insulin release level.blood pressure, blood─lipid.and the relations of them in 30 normal persons and30 patients with coronary atherosclerotic heart dis-ease(CHD).Tbe results Showed that CHD patients had low OGTT,high TC,TG&LDL─C,andlow HDL─C. There was obvious difference in the patients compared with the normal people(P<0.05 or 0.01).The results clearly showed that insulin resistance is one of the independent dangerousfactors in CHD patients. Therefore ,to regulate diet,increase physical exercise,decrease BMI,and re-duce the insulin resistanec of the body is one of the extraordinaryly important ways to prevent andtreat CHD.