| ^153Sm-EDTMP与中草药联合治疗骨转移癌骨痛的近期临床观察 |
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| 引用本文： | 周海中,朱健泉,王馨然.^153Sm-EDTMP与中草药联合治疗骨转移癌骨痛的近期临床观察[J].临床医学,2009,29(1):112-113. |
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| 作者姓名： | 周海中 朱健泉 王馨然 |
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| 作者单位： | 扬州大学临床医学院,江苏扬州,225001 |
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| 摘 要： | 目的利用中草药与^153Sm-EDTMP联合治疗骨转移癌，以提高^153Sm-EDTMP的疗效和减轻其骨髓抑制的副作用。方法选择经临床和病理确诊为肿瘤的患者54例，随机分为A、B两组进行研究。A组即^153Sm-EDTMP治疗组，30例；B组即^153Sm-EDTMP＋中草药治疗组，24例。^153Sm-EDTMP用量为37—74MBq／kg，中草药选用祛风通络、除湿解毒、益肾补气填精之类。结果A组疼痛缓解和生活质量的改善分别为80％和86．1％，外周血白细胞在用药2周后明显下降（P〈0．05），血小板在用药后1个月明显下降（P〈0．05）；B组疼痛缓解和生活质量的改善分别为91．7％和95．8％，外周血象未见明显改变。结论中草药和^153Sm-EDTMP联合治疗骨转移癌具有临床应用价值。
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| 关 键 词： | 骨转移癌 草药 钐 乙二胺甲撑膦酸 |
Treating metastatic carcinoma of bone with integrated herds and Samarium-~(153)Sm-EDTMP |
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| ZHOU Haizhong,ZHU Jianquan,WANG Qingran.Treating metastatic carcinoma of bone with integrated herds and Samarium-~(153)Sm-EDTMP[J].Clinical Medicine,2009,29(1):112-113. |
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| Authors: | ZHOU Haizhong ZHU Jianquan WANG Qingran |
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| Institution: | ZHOU Haizhong,ZHU Jianquan,WANG Qingran.Clinical Medical College,Yangzhou University,Yangzhou 225001,China |
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| Abstract: | Objective To improve anti-pain efficiency of 153Sm-EDTMP and reduce its adverse side-effect of marrow suppression,herbs were used to treat metastatic carcinoma of bone with 153Sm-EDTMP. Methods The patients were classified into two groups,group A:30 patients were treated only with 153Sm-EDTMP;group B:24 patients were treated with 153Sm-EDTMP and herds.The administered amount of 153Sm-EDTMP was 37-74 MBq/kg in groups of patients.The herbs include drugs for expelling wind,promoting blood circulation and resto... |
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| Keywords: | Bone metastases Herds Samarium EDTMP |
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