胃肠肿瘤根治联合肝移植术治疗晚期胃肠肿瘤并肝脏广泛转移

目的 总结胃肠肿瘤根治联合肝移植治疗晚期胃肠肿瘤并发肝脏多发转移的近期疗效。方法 1例胃癌和2例直肠癌并发肝脏多发转移患者，分别接受胃癌和直肠癌根治、联合原位同种异体肝移植手术，其中1例因肺结核同时行左上肺部分切除术。结果 3例患者无围手术期死亡。随访5-7个月，胃癌患者术后5个月死于肿瘤复发；1例直肠癌并肺结核患者术后7个月死于肝功能衰竭，无肿瘤复发；另1例直肠癌患者已完成3个月化疗，术后半年无复发，肝功能和血常规正常，精神食欲好，已恢复工作。结论 胃肠肿瘤根治联合肝移植为部分晚期肿瘤患者提供了生存的希望，远期效果有待进一步观察。

Radical resection of gastric or colorectal carcinoma combined with liver transplantation for gastric or colorectal carcinoma with multiple hepatic metastases

Objective To summarize the short-term outcomes of radical resection of gastric or colorectal carcinoma combined with liver transplantation for gastric or colorectal carcinoma with multiple hepatic metastases. Methods Radical resection of gastric or colorectal carcinoma combined with liver transplantation were performed on one gastric carcinoma case and two rectal carcinoma cases with severe liver metastasis, and partial resection of left lung was performed in one of the two rectal cancer cases for pulmonary tuberculosis. Results There was no perioperative death. The gastric cancer patient died of recurrence 5 months after operation. The rectal cancer patient with pulmonary tuberculosis died of hepatic function failure 7 months after operation without recurrence. Another rectal cancer patient recovered well with normal liver functions, blood cells, without recurrence signs, and was back to work. Conclusion Radical operation combined with liver transplantation may provide survival opportunity for some patients with gastric or colorectal carcinoma synchronous with severe liver metastasis, but the long-term outcome needs to be observed.