Widespread abdominal venous thrombosis in paroxysmal nocturnal hemoglobinuria diagnosed on CT |
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| Authors: | G Gayer G Zandman-Goddard P Raanani M Hertz S Apter |
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| Institution: | (1) Department of Diagnostic Imaging, Sheba Medical Center, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Tel Hashomer 52621, Israel, IL;(2) Department of Internal Medicine B, Sheba Medical Center, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Tel Hashomer 52621, Israel, IL;(3) Institute of Hematology, Sheba Medical Center, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Tel Hashomer 52621, Israel, IL |
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| Abstract: | Paroxysmal nocturnal hemoglobinuria is a rare disorder characterized by pancytopenia. One of the main manifestations of this
disease is development of widespread life-threatening venous thrombosis, which may involve multiple abdominal veins. We describe
two patients with paroxysmal nocturnal hemoglobinuria with clinically unsuspected portal, splenic, and mesenteric venous thromboses
that were diagnosed on computed tomography. This complication should be clinically suspected in patients suffering from paroxysmal
nocturnal hemoglobinuria who present with abdominal pain, and it should be sought by the radiologist on pre- and postcontrast
computed tomography.
Received: 3 October 2000/Accepted: 15 November 2000 |
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| Keywords: | : Paroxysmal nocturnal hemoglobinuria— Portal vein thrombosis— Mesenteric vein thrombosis |
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