盆底肌电刺激对羊尿道功能影响的实验研究

目的　探讨盆底肌电刺激对尿道功能的影响。　方法　将 18只羊随机分为实验和对照两组 ,实验组施以电流刺激盆底肌 ,对照组只放置电极而不予通电 ,其余条件相同。观察尿动力学及生化等指标变化。　结果　实验组尿道控制带刺激前 2 .4 3cm ,刺激后 2 .6 2cm ,延长 7.8% (P <0 .0 5 ) ;最大尿道压刺激前 2 2 .7cmH2 O(1cmH2 O =0 .0 98kPa) ,刺激后 2 3.4cmH2 O ,升高 6 .8% (P<0 .0 5 ) ;膀胱颈压前、后变化不明显。对照组放置电极前后比较差别无显著性意义 (P >0 .0 5 )。生化检查见刺激组尿道外括约肌核酸总量前∶后 =1.2 1∶1.2 5、收缩电解质Ca2 /Mg3 前∶后 =1.71∶1.82、Ca2 /Pi3 前∶后 =1.0 9∶1.15及cAMP前∶后 =1.6 0∶1.6 8,均显著增高 (P <0 .0 5 )。电镜检查见实验组线粒体、溶酶体明显增多 (约 2 .2倍 )。雌雄动物之间差别无显著性意义 (P >0 .0 5 )。　结论　电刺激可增强尿道控尿能力 ,对压力性尿失禁有肯定的治疗价值

An experimental study on the influence of electrical pelvic floor stimulation to the goats'''' urethral function

Objective To observe the goats' urethral urodynamic and biochemical changes after electrical pelvic floor stimulated. Methods 18 goats were randomized into the stimulating group with pelvic floor stimulation and the control group. Results After being stimulated,the urethral continence length significantly increased by 7.8%( P <0.05),the maximum urethral pressure significantly increased by 6.8%( P <0.05),and the metabolic level of the urethral sphincter cells significantly elevated( P <0.05).While these did not occur in the control group. Conclusions The electric stimulation could enhance the urethral continence.So,it might be helpful to patients with stress incontinence.