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柴胡桂枝汤对离体蟾蜍坐骨神经动作电位的影响
引用本文:李旭伟,李婷婷,胡馨予,罗丹,张涛,岳泉吉.柴胡桂枝汤对离体蟾蜍坐骨神经动作电位的影响[J].四川生理科学杂志,2014(1):10-12.
作者姓名:李旭伟  李婷婷  胡馨予  罗丹  张涛  岳泉吉
作者单位:[1]川北医学院基础医学院机能实验中心,四川南充637000 [2]川北医学院临床医学系,四川南充637000
基金项目:川北医学院2013年大学生科研项目
摘    要:目的:研究柴胡桂枝汤对蟾蜍离体坐骨神经干动作电位传导阻滞作用。方法:观察柴胡桂枝汤对蟾蜍离体坐骨神经复合动作电位的振幅和传导速度的影响。结果:柴胡桂枝汤作用0min、2min、4min、6min、8min、10min后均使坐骨神经干复合动作电位的振幅变小(P0.01),传导速度变慢(P0.01)并最终使坐骨神经动作电位消失。结论:柴胡桂枝汤能阻滞神经动作电位的传导。

关 键 词:柴胡桂枝汤  离体蟾蜍坐骨神经  复合动作电位  传导阻滞

Effects of radix bupleuri cassia twig on compound action potential of sciatic nerveof toad
Li Xu-wei Li Ting-ting Hu Xing-yu Luo Dan Zhang Tao Yue Quan-ji.Effects of radix bupleuri cassia twig on compound action potential of sciatic nerveof toad[J].Sichuan Journal of Physiological Sciences,2014(1):10-12.
Authors:Li Xu-wei Li Ting-ting Hu Xing-yu Luo Dan Zhang Tao Yue Quan-ji
Institution:Li Xu-wei Li Ting-ting Hu Xing-yu Luo Dan Zhang Tao Yue Quan-ji(1. Functional Center, School of Preclinical Medicine, North Sichuan Medical, Sichuan Nanchong 637007; 2. Department of Clinical Medicine,North Sichuan Medical, Sichuan Nanchong 637007)
Abstract:Objective: To study the blockade effect of radix bupleuri cassia twig on action potential of sciatic nerve of toad. Methods: The influence of radix bupleuri cassia twig on amplitude and conduction velocity of compound action potential of sciatic nerve of toad was observed in vitro. Results: The decoction of radix bupleuri cassia twig sustain affect in seven different times (0 min, 2 rain, 4 rain, 6 rain, 8 rain, 10 min) could decrease the amplitude (P〈0. 01) and slow down the conduction velocity (P〈0. 01). The action potential of sciatic nerve vanished at last. Condusion: Radix bupleuri cassia twig can block the conduction of action potential of nerve.
Keywords:Radix bupleuri cassia twig  Sciatic nerve of toad in vitro  Compound action potential  Blockade
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