| 手足口病患儿血清心肌酶和超敏C反应蛋白的临床应用 |
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| 引用本文： | 曾兰兰,顾晓琼,刘非,陈小娟,黄玉开,梁肖云,龙海锋,李娟.手足口病患儿血清心肌酶和超敏C反应蛋白的临床应用[J].热带医学杂志,2014(8):1038-1040. |
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| 作者姓名： | 曾兰兰 顾晓琼 刘非 陈小娟 黄玉开 梁肖云 龙海锋 李娟 |
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| 作者单位： | 广州市妇女儿童医疗中心检验科,广东广州510623 |
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| 基金项目： | 广东省自然科学基金（S2013010012520） |
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| 摘 要： | 目的探讨心肌酶和超敏C反应蛋白(hs-CRP)在手足口病患儿血清中的变化规律及其诊疗价值。方法应用日立7600全自动生化分析仪检测50例手足口病患儿的血清心肌酶和hs-CRP,并与30名健康体检儿童作对照。结果手足口病患儿乳酸脱氢酶、肌酸激酶、肌酸激酶同工酶、α-羟丁酸脱氢酶和hs-CRP在血清中的含量分别为(350.98±82.52)U/L、(177.36±130.29)U/L、(40.74±9.91)U/L、(281.14±68.05)U/L和(23.74±22.65)mg/L,异常率分别为52.0%、14.0%、56.0%、24.0%和76.0%,均高于对照组,差异有统计学意义(P0.05)。结论及时检测手足口病患儿血清心肌酶和hs-CRP能尽早发现其心肌损伤情况,指导临床诊疗。
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| 关 键 词： | 手足口病 心肌酶 超敏C反应蛋白 |
Clinical application of myocardial enzymes and high-sensitivity C-reactive protein in children with hand-foot and mouth disease |
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| ZENG Lan-lan,GU Xiao-qiong,LIU Fei,CHEN Xiao-juan,HNANG Yu-kai,LIANG Qiao-yun,LONG Hai-feng,LI Juan.Clinical application of myocardial enzymes and high-sensitivity C-reactive protein in children with hand-foot and mouth disease[J].Journal Of Tropical Medicine,2014(8):1038-1040. |
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| Authors: | ZENG Lan-lan GU Xiao-qiong LIU Fei CHEN Xiao-juan HNANG Yu-kai LIANG Qiao-yun LONG Hai-feng LI Juan |
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| Institution: | (Clinical Laboratory, Guangzhou Women and Children＇s Medical Center, Guangdong, Guanghou 510623, China) |
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| Abstract: | Objective To discuss the clinical application of myocardial enzymes and high-sensitivity C-reactive protein in the children with hand-foot and mouth disease. Methods The serum myocardial enzymes including LDH, CK, CK-MB, α-HBDH and hs-CRP were detected by Hitachi 7600 automatic biochemical analyzer to detect in 50 cases with HFMD and 30 healthy control group. Results The concentration and abnormal rate of serum myocardial enzymes and high-sensitivity C-reactive protein in the HFMD group were significantly higher than those in the control groups（P〈0.05）. Conclusion Myocardial enzymes and hs-CRP could be used as a valuable marker to predict prognosis of myocardial injury in the children with HFMD. |
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| Keywords: | hand-foot and mouth disease myocardial enzyme high sensitivity c-reactive protein |
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