青年急性冠脉综合征患者临床特点的回顾性分析

目的探讨青年急性冠状动脉综合征(acute coronary syndrome,ACS)的临床特点。方法选取≤45岁ACS患者174例为青年ACS组,同期60~75岁ACS患者191例为老年ACS组,比较两组患者的危险因素、临床特点、冠脉病变特征及主要心血管不良事件。结果青年ACS患者中男性、超重/肥胖、吸烟者比例、总胆固醇、甘油三酯尿酸水平以及低高密度脂蛋白水平高于老年组。青年ACS组中ST段抬高心肌梗死占比最高,老年ACS组中不稳定心绞痛占比最高,组间比较差异有统计学意义(P<0.05)。结论青年ACS患者多为男性,超重/肥胖、吸烟和血脂异常、ST段抬高心肌梗死在青年ACS患者中占优势,主要不良心血管事件发生率和老年患者无差异。

A retrospective analysis of clinical features of young adults with acute coronary syndrome

Objective To investigate the epidemiology,clinical feature and angiographic characteristics of young adults with acute coronary syndrome(ACS).Methods A retrospective study of 174 ACS patients under the age of 45 years old and 191 ACS patients between the ages of 60 to 75 years old was performed.Risk factors,clinical features,angiographic characteristics,and incidence of major adverse cardiovascular events were analyzed.Results Male,overweight/obesity,and smoking were more common in the ACS patients under 45 years old.The level of total cholesterol,triglyceride,low density lipoprotein,uric acid levels and low HDL lipoprotein was higher in the elderly ACS patients when compared to the young ACS patients.ST segment elevation myocardial infarction was the most often presentation in the young ACS patients while the highest proportion of unstable angina pectoris was found in the elderly ACS patients.Conclusion The population of young patients with ACS is predominantly male.The most important risk factors are overweight/obesity,smoking behavior,and dyslipidemia.ST segment elevation myocardial infarction was the most common presentation in the young ACS patients.Incidence of major adverse cardiovascular events between the two groups was similar during hospitalization.