认知行为疗法对医学难以解释的躯体症状干预效果的Meta分析

目的评价认知行为疗法对医学难以解释的躯体症状的干预效果。方法计算机检索Cochrane图书馆、Pubmed、Embase、中文期刊全文数据库(CNKI)、万方、维普数据库中的随机对照实验,干预措施为认知行为疗法。严格质量评价后,采用RevMan5.4进行数据分析。使用标准化均数差计算试验的效应大小,并用I2检验评估样本的异质性。结果最终纳入9项研究,共计1035名研究对象。Meta分析结果显示,认知行为疗法可以缓解医学难以解释的躯体症状SMD=-0.33(n=1035,CI=-0.45-0.20),P<0.001。结论认知行为疗法能对医学难以解释的躯体症状产生有效干预。

The intervention effect of cognitive behavior therapy for medically unexplained symptoms:a meta-analysis of randomized controlled trials

Objective To evaluate the intervention effect of cognitive behavioral therapy(CBT)for medically unexplained somatic symptoms.Methods The randomized controlled trials in Cochrane Library,MEDLINE,EMBASE and other databases were searched by computer.After strict quality evaluation,Revman5.4 was used for data analysis.The standardized mean difference was used to calculate the effect size of the test,and I2 test was used to evaluate the heterogeneity of samples.Results Nine studies involving 1,035 subjects were included.Meta analysis showed that cognitive behavioral therapy could relieve medically inexplicable physical symptoms[SMD=-0.33(n=1035,CI=-0.45-0.20),P<0.001].Conclusion Cognitive behavioral therapy can provide an effective intervention for patients with medically inexplicable physical symptoms.It is suitable for clinical application.