列线图预测经翼点入路夹闭破裂前循环动脉瘤患者的预后

目的 探讨影响经翼点入路夹闭破裂前循环动脉瘤患者预后的因素,构建预测患者预后情况的列线图模型.方法 选择六安市中医院收治的71例前循环动脉瘤破裂的患者,均采用经翼点入路夹闭术治疗.术后6个月采用格拉斯哥预后评级(GOS)评估患者预后,Ⅰ～Ⅲ级纳入预后不良组,Ⅳ～Ⅴ级纳入预后良好组.采用多因素logistic回归筛选影响...

A nomogram predicts the prognosis of patients with ruptured anterior circulation aneurysms after clipping surgery via the pterional approach

Objective To analyze the factors affecting the prognosis of patients with ruptured anterior circulation aneurysms after clipping surgery via the pterional approach,and construct a nomogram model for predicting the prognosis of the patients.Methods A total of 71 patients with ruptured anterior circulation aneurysms after clipping surgery via the pterional approach in our hospital were recruited.The prognosis of the patients after 6 months of surgery was evaluated by the Glasgow outcome scale(GOS).Patients with gradeⅠ~Ⅲwere included in poor outcome group,and those with gradeⅣ~Ⅴwere in good outcome group.Multivariate logistic regression was used to screen independent risk factors that affect the prognosis of the patients,and a nomogram was established to predict the risks of poor outcome in these patients.Results There were 12 cases(16.90%)in the poor outcome group and 59 cases(83.10%)in the good outcome group.Multivariate logistic regression analysis showed that age,IL-6,neutrophil to lymphocyte ratio(NLR),modified Fisher score and Hunt-Hess classification were independent influencing factors for the prognosis of the patients.The nomogram established based on the above factors showed good discrimination(AUC=0.916)and calibration(χ2=9.125,P=0.362),indicating an accurate prediction for the risk of poor outcome.Conclusion The nomogram can accurately predict the risk of poor outcome in patients with ruptured anterior circulation aneurysms after clipping surgery via the pterional approach.It helps to take timely preventive measures to improve the prognosis of the patients.