| 动脉粥样硬化中内皮间充质转化的研究进展 |
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| 引用本文： | 田睿,蒋晨,陈新忠. 动脉粥样硬化中内皮间充质转化的研究进展[J]. 医学分子生物学杂志, 2022, 19(3): 261-264. DOI: 10.3870/j.issn.1672-8009.2022.03.015 |
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| 作者姓名： | 田睿 蒋晨 陈新忠 |
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| 作者单位： | 华中科技大学同济医学院附属协和医院心脏大血管外科 武汉市, 430000 |
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| 摘 要： | 内皮细胞是心脏、 血管、 淋巴管等器官组织的重要组成部分, 在心血管系统生理过程中起至关重要作用。 内皮间充质转化 (endothelial-mesenchymal transition, EndMT) 调控内皮细胞向间充质细胞转化,其参与动脉粥样硬化过程。 EndMT 可能为动脉粥样硬化的防治提供新靶点与思路。
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| 关 键 词： | 内皮间充质转化 动脉粥样硬化 |
Research Progresson Roles of Endothelial-mesenchymal Transforma-tion in Atherosclerosis |
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| TIAN Rui,JIANG Chen,CHEN Xinzhong. Research Progresson Roles of Endothelial-mesenchymal Transforma-tion in Atherosclerosis[J]. Journal of Medical Molecular Biology, 2022, 19(3): 261-264. DOI: 10.3870/j.issn.1672-8009.2022.03.015 |
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| Authors: | TIAN Rui JIANG Chen CHEN Xinzhong |
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| Affiliation: | Department of Cardiac Surgery, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China |
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| Abstract: | Endothelial cells are important components of the heart, blood vessels and lymphvessels. They play a crucial role in regulating the physiological processes of the cardiovascularsystem. Endothelial-mesenchymal transition (EndMT) is the transition of endothelial cells to mesenchymal cells, and it has been reported to be involved in atherosclerosis. Various cytokines arechanged during the process of EndMT. The study of EndMT may provide insight for the mechanismand treatment of atherosclerosis. |
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| Keywords: | endothelial-mesenchymal transition atherosclerosis |
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