Association between circulating level of CD40 ligand and angiographic morphologic features indicating high-burden thrombus formation in patients with acute myocardial infarction undergoing primary coronary intervention. |
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| Authors: | Ali A Youssef Li-Teh Chang Jiunn-Jye Sheu Fan-Yen Lee Sarah Chua Kuo-Ho Yeh Cheng-Hsu Yang Chiung-Jen Wu Hon-Kan Yip |
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| Institution: | Cardiology Department, Suez Canal University Hospital, Ismailia, Egypt. |
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| Abstract: | BACKGROUND: This study tested the hypothesis that in the acute phase of myocardial infarction (MI), the circulating level of soluble CD40 ligand (sCD40L), an index of platelet activation, is predictive of angiographic morphologic features that indicate high-burden thrombus formation (HBTF) in the infarct-related artery (IRA). METHODS AND RESULTS: This prospective study included 162 consecutive patients: 64 with HBTF and 98 with low-burden thrombus formation (LBTF). All patients had a Killip's classification
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