qnrA in CTX-M-producing Escherichia coli isolates from France |
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Authors: | Lavigne Jean-Philippe Marchandin Hélène Delmas Julien Bouziges Nicole Lecaillon Evelyne Cavalie Laurent Jean-Pierre Hélène Bonnet Richard Sotto Albert |
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Institution: | Laboratoire Universitaire d'Antibiologie, UFR de Médecine, Avenue Kennedy, 30908 N?mes Cedex 02, France. |
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Abstract: | By PCR, we screened for qnr genes 112 clinical isolates of extended-spectrum beta-lactamase-producing Escherichia coli collected from hospitals in France during 2004. For the first time, 7.7% of CTX-M-producing E. coli isolates presented a plasmid-mediated resistance to quinolones. All strains harbored a qnrA gene located on a sul1-type class 1 integron with similar structure to the In36 integron. |
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