骨原发性非何杰金氏淋巴瘤临床及X线表现(附14例报告)

目的探讨原发性骨非何金淋巴瘤临床及X线表现,为临床诊断和治疗提供有价值的信息.方法回顾性分析和总结了14例经临床及病理证实发生于骨的原发性非何杰金淋巴瘤的临床及X线资料,其中男9例,女5例,平均年龄35岁,病程平均11个月.结果14例中,单发病灶11例,多发病灶3例,病变多发于扁骨及长骨的骨端,X线表现为骨质破坏的同时伴有部分边缘轻度硬化,可侵及关节面,破坏关节,可出现骨膜反应及软组织肿块.骨质破坏分为溶骨型(n=8)、成骨型(n=2)、囊状扩张型(n=3)及混合型(n=1)四大类.结论骨原发性非何杰金氏淋巴瘤有其相对特征性的X线表现,再结合临床有关资料,可望提高该病的准确诊断率.

The Clinical and X - ray Manifestations of Primary Non - Hodgkin'''' s Lymphoma of Bone(An Analysis of 14 Cases)

Objective To study the clinical and X-ray manifestations of primary non-Hodgkin's lymphoma(PNHL)of bone so that to suppy the valuable informations for clinical diagnosis and treatment of this disease.Methods 14 cases with PNHL of bone confirmed by clinic and pathology were analyzed retrospectively.There were 9 male and 5 femal,age ranged from 20 to 60 years with average of 35 years,and average history of disease was 11 months in all cases.Results Of all cases single bone involved in 11 cases,multiple bone involved in 3 cases,most of them the flat bone and the distal end of long bone were involved.The appearances of the lesion on X-ray were bony destruction with slight sclerosis at the margin of destructive area,there were periosteal reaction,soft tissue masses and destruction of joint manifestations,PNHL of bone can be classified as four typers:osteolytic(n=8),sclerotic(n=2),mixed(n=3)and cystic(n=1)lesions by the form and feature of bone destruction.Conclusion PNHL of bone has characteristic X-ray manifestations comparatively.The correct diagnostic rate can be improved if we concern about clinical data.