Cardiac risk after craniopharyngioma therapy |
| |
Authors: | Mong Sandy Pomeroy Scott L Cecchin Frank Juraszek Amy Alexander Mark E |
| |
Affiliation: | Harvard Medical School, Boston, Massachusetts, USA. sandy_mong@hms.harvard.edu |
| |
Abstract: | Although long-term survival after craniopharyngioma treatment is excellent in childhood and early adulthood, sudden deaths in two craniopharyngioma survivors with cardiac findings suggest a need to determine whether treated patients exhibit potential substrates for sudden cardiac death. We present a retrospective review of two index patients with cardiac mortality. This motivated a prospective cardiac screening of 12 survivors that identified nearly a third with significant QTc prolongation. QTc-prolonging medication and stimulants should be used with caution in this population, and routine electrocardiogram screening may identify those at highest risk. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|