副肿瘤性天疱疮的超声及CT特征

目的 探讨副肿瘤性天疱疮（PNP）的超声及CT特征与临床表现。方法 回顾性分析手术病理证实的8例副肿瘤性天疱疮患者完整的临床、实验室、影像学、病理学及术后随访资料。结果 8例副肿瘤性天疱疮主要临床特征和超声、CT表现综合归纳为：多形性皮肤损害伴疼痛性黏膜糜烂溃疡，同时合并内脏软组织肿块。肿瘤部位：腹膜后6例，胸腔纵隔2例。病理类型：巨淋巴结增生7例，非霍奇金淋巴瘤1例。结论 超声及CT可以发现副肿瘤性天疱疮时皮肤黏膜损害出现之前的内脏肿瘤，且应首选腹部超声检查，其次是胸部CT。

Ultrasound and CT features of paraneoplastic pemphigus

Objective To investigate the clinical feature as well as ultrasound and CT characteristics of paraneoplastic pemphigus(PNP).Methods Total datum of the clinical,laboratory,imaginology,histopathology and the follow-up observations of 8 PNP cases those were finally confirmed by operation were analyzed retrospectively.Results The clinical characteristics as well as ultrasound and CT findings of the 8 PNP cases were summaried as follows:polymorphous cutaneous impairments and painful mucous erosion and ulceration were all companied by visceral neoplasms with 6 of which arise from retroperitoneum and 2 from mediastinum.Histopathologic classifications were 7 Castleman's disease and 1 non-Hodgkin's lymphoma.Conclusions Vesceral neoplasm often occurs before mucocutaneous impairments in PNP patients,as one of diagnostic procedures,abdominal sonography is the first choice,the second is chest CT.