Cerebral and systemic amino acid metabolism in experimental acute amphetamine poisoning in guinea pigs |
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| Authors: | A. Bondoli S. Barbi F. Rodola D. Camaioni A. Gagliardi S.I. Magalini |
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| Affiliation: | Facoltà di Medicina e Chirurgia, Istituto di Anestesiologia e Rianimazione, Uniuersitá Cattolica del Sacro Cuore, Via delle Pineta Sacchetti 644, Rome 00168 Italy |
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| Abstract: | Protein catabolism, as measured by plasma amino acids is increased by amphetamine injection (15 mg/kg body wt) administered to 10 adult male guinea pigs. Changes in the cerebrospinal fluid were less marked than those in the plasma. The amphetamine seemed to inhibit the enzymes of the metabolic pathways that use amino acids. |
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