| 颞下颌关节紊乱综合征关节液白细胞介素1活性及其临床意义 |
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| 引用本文： | 傅开元,马绪臣,张震康,庞学文,陈慰峰. 颞下颌关节紊乱综合征关节液白细胞介素1活性及其临床意义[J]. 北京大学学报(医学版), 1993, 0(6) |
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| 作者姓名： | 傅开元 马绪臣 张震康 庞学文 陈慰峰 |
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| 作者单位： | 北京医科大学口腔医学院颌面外科(傅开元，马绪臣，张震康)，北京医科大学基础医学院免疫学教研室(庞学文)，北京医科大学基础医学院免疫学教研室(陈慰峰) |
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| 摘 要： | 采用传代淋巴细胞株LBRM33-IA 5和HT-2,检测了36例颞下颌关节紊乱综合征(TMJDS)关节液中IL-1活性,发现TMJDS关节液中检测到IL-1活性,且器质性改变类患者关节液IL-1活性明显高于肌肉功能紊乱类及结构紊乱类。结果提示,IL-1参与了TMJDS关节组织的病理破坏过程。
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| 关 键 词： | 颞下颌关节 关节液 细胞因子 |
INTERLEUKIN-1 ACTIVITY IN SYNOVIAL FLUIDS OF TEMPOROMANDIBULAR JOINT DISTURBANCE SYNDROME |
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| Fu Kaiyuan,et al College of Stomatology. INTERLEUKIN-1 ACTIVITY IN SYNOVIAL FLUIDS OF TEMPOROMANDIBULAR JOINT DISTURBANCE SYNDROME[J]. Journal of Peking University. Health sciences, 1993, 0(6) |
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| Authors: | Fu Kaiyuan et al College of Stomatology |
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| Abstract: | Using murine T cell close LBRM33-IA5 and HT-2, interleukin 1 (IL-1) biological activity insynovial fluids of the patients with Temporomandibular Joint Disturbance Syndrome (TMJDS) wastested. The results demonstrate that IL-1 activity is much higher in the cases with TMJ degenerativechanges than the cases with Masticatory Muscle Disorder and the cases with TMJ Disc Displacement.The findings suggest that IL-1 and IL-1 inhibitors present in synovial fluids of TMJDS, and contributeto joint destruction. |
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| Keywords: | Temporomandibular joint Synovial fluid Cytokine |
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